A-154 Chromosome 18q Deletion & Chromosome 18p Duplication: A Neuropsychological Case Study

Abstract Objective: The client presents with partial deletion of chromosome 18q and duplication 18p, occurring in 1 55,000 individuals less than 1,000,000 individuals, respectively. Deletions are often characterized by hypotonia, seizures, psychomotor retardation, intellectual disability. Duplications 18p disability, epilepsy, developmental delay, attention deficits. Method: is a 5-year-old male, who was diagnosed the above-mentioned genetic disorders Chiari malformation at age 2. Additionally, speech delay low muscle tone. client’s parents sought testing to clarify his cognitive emotional functioning light inform treatment supports. Results: Nonverbal assessment average range. Academic achievement noted reading skills, impaired math abilities, borderline spelling. Neuropsychologically, impairments were verbal memory, simple auditory attention, semantic fluency, visual perception, motor coordination, integration, affect recognition. Mild moderate inefficiencies comprehension instructions, response inhibition, fine dexterity, perspective taking. Otherwise, performed range on tasks behavioral inhibition persistence, expressive language, receptive language. Conclusions: Given limited literature, it expected these will be associated disabilities attentional difficulties. However, IQ range, he potential learning reading, writing, mathematics visual-motor, social perception